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There are hundreds of soybean varieties with resistance against the soybean cyst nematode (SCN). Most of the varieties available for Iowa in the last several decades have had resistance genes from a breeding line called PI 88788. SCN resistance from PI 88788 is losing or has lost its effectiveness. Farmers should grow soybean varieties with other sources of resistance, if possible. This article lists soybean varieties available for 2021 in Iowa with resistance sources that are different from PI 88788.